PDBe 6ero

X-ray diffraction
1.75Å resolution

Structure of human TFB2M

Released:
Source organism: Homo sapiens
Primary publication:
Structural Basis of Mitochondrial Transcription Initiation.
Cell 171 1072-1081.e10 (2017)
PMID: 29149603

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dimethyladenosine transferase 2, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 313 amino acids
Theoretical weight: 35.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H5Q4 (Residues: 63-341, 348-396; Coverage: 66%)
Gene names: NS5ATP5, TFB2M
Sequence domains: Ribosomal RNA adenine dimethylase

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 43.95Å b: 165.65Å c: 44.73Å
α: 90° β: 97.97° γ: 90°
R-values:
R R work R free
0.193 0.192 0.214
Expression system: Escherichia coli BL21(DE3)