PDBe 6eqi

X-ray diffraction
3.1Å resolution

Structure of PINK1 bound to ubiquitin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ubiquitin Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P0CG48 (Residues: 609-684; Coverage: 11%)
Gene name: UBC
Sequence domains: Ubiquitin family
Nb696 Chain: B
Molecule details ›
Chain: B
Length: 134 amino acids
Theoretical weight: 14.53 KDa
Source organism: Lama glama
Expression system: Escherichia coli
Serine/threonine-protein kinase PINK1, putative Chain: C
Molecule details ›
Chain: C
Length: 433 amino acids
Theoretical weight: 49.88 KDa
Source organism: Pediculus humanus corporis
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW E0W1I1 (Residues: 143-575; Coverage: 75%)
Gene names: 8239562, Phum_PHUM577390
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P3121
Unit cell:
a: 105.711Å b: 105.711Å c: 149.451Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.203 0.234
Expression system: Escherichia coli