PDBe 6eje

X-ray diffraction
2.43Å resolution

Human Xylosyltransferase 1 in complex with peptide PAAEGSGEQDFT


Function and Biology Details

Reaction catalysed:
UDP-alpha-D-xylose + [protein]-L-serine = UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Xylosyltransferase 1 Chain: A
Molecule details ›
Chain: A
Length: 751 amino acids
Theoretical weight: 86.12 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
  • Canonical: Q86Y38 (Residues: 232-959; Coverage: 76%)
Gene names: XT1, XYLT1
Sequence domains:
Syndecan-1 Chain: B
Molecule details ›
Chain: B
Length: 12 amino acids
Theoretical weight: 1.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P18827 (Residues: 201-212; Coverage: 4%)
Gene names: SDC, SDC1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 67.28Å b: 86.72Å c: 153.47Å
α: 90° β: 90° γ: 90°
R R work R free
0.199 0.197 0.235
Expression systems:
  • Homo sapiens
  • Not provided