PDBe 6c97

X-ray diffraction
2Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IgG receptor FcRn large subunit p51 Chains: A, C
Molecule details ›
Chains: A, C
Length: 274 amino acids
Theoretical weight: 30.41 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P55899 (Residues: 24-297; Coverage: 80%)
Gene names: FCGRT, FCRN
Sequence domains:
Beta-2-microglobulin Chains: B, D
Molecule details ›
Chains: B, D
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 42.1Å b: 76.25Å c: 140.15Å
α: 90° β: 93.75° γ: 90°
R-values:
R R work R free
0.176 0.174 0.21
Expression system: Trichoplusia ni