PDBe 6b6u

X-ray diffraction
1.35Å resolution

Pyruvate Kinase M2 mutant - S437Y


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Pyruvate kinase PKM Chains: A, B
Molecule details ›
Chains: A, B
Length: 525 amino acids
Theoretical weight: 57.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: NEW P14618 (Residues: 7-531; Coverage: 99%)
Gene names: OIP3, PK2, PK3, PKM, PKM2
Sequence domains:

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: C2
Unit cell:
a: 110.35Å b: 93.61Å c: 109.36Å
α: 90° β: 95.64° γ: 90°
R R work R free
0.131 0.13 0.149
Expression system: Escherichia coli