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Crystal Structure of PML RING tetramer

X-ray diffraction
1.6Å resolution
PDB entry 5yuf coloured by chain, front view.
PDB entry 5yuf coloured by chain, side view.
PDB entry 5yuf coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein PML
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Multimeric state: homo tetramer
Accessible surface area: 11168.8 Å2
Buried surface area: 4071.81 Å2
Dissociation area: 645.74 Å2
Dissociation energy (ΔGdiss): -0.92 kcal/mol
Dissociation entropy (TΔSdiss): 10.82 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-151547

Macromolecules

Protein PML
Chains: A, B, C, D
Length: 51 amino acids
Theoretical weight: 5.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29590 (Residues: 49-99; Coverage: 6%)
Gene names: MYL, PML, PP8675, RNF71, TRIM19
Pfam: Zinc finger, C3HC4 type (RING finger)
InterPro:
Protein PML in PDB entry 5yuf, assembly 1, front view.
Protein PML in PDB entry 5yuf, assembly 1, side view.
Protein PML in PDB entry 5yuf, assembly 1, top view.
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