Assemblies
Assembly Name:
Epidermal growth factor receptor
Multimeric state:
monomeric
Accessible surface area:
15028.67 Å2
Buried surface area:
131.78 Å2
Dissociation area:
65.89
Å2
Dissociation energy (ΔGdiss):
10.12
kcal/mol
Dissociation entropy (TΔSdiss):
-0.83
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-132671
Macromolecules
Chain: A
Length: 327 amino acids
Theoretical weight: 37.35 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 327 amino acids
Theoretical weight: 37.35 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P00533 (Residues: 696-1022; Coverage: 28%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Tyrosine-protein kinase, catalytic domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
