PDBe 5w0n

X-ray diffraction
2.5Å resolution

Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
UTP + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Terminal uridylyltransferase 7 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 403 amino acids
Theoretical weight: 46.66 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: NEW Q5VYS8 (Residues: 963-1365; Coverage: 27%)
Gene names: HS2, KIAA1711, TUT7, ZCCHC6
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P61
Unit cell:
a: 135.972Å b: 135.972Å c: 181.574Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.187 0.215
Expression system: Spodoptera frugiperda