Assemblies
Assembly Name:
Coagulation factor VIIa complex
Multimeric state:
hetero dimer
Accessible surface area:
13268.75 Å2
Buried surface area:
3556.12 Å2
Dissociation area:
1,059.48
Å2
Dissociation energy (ΔGdiss):
7.99
kcal/mol
Dissociation entropy (TΔSdiss):
10.75
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-140351
Macromolecules
Chain: H
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
Pfam: Trypsin
InterPro:
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
- Canonical:
P08709 (Residues: 213-466; Coverage: 57%)
Pfam: Trypsin
InterPro:
- Serine proteases, trypsin domain
- Peptidase S1, PA clan
- Peptidase S1, PA clan, chymotrypsin-like fold
- Peptidase S1A, chymotrypsin family
- Serine proteases, trypsin family, histidine active site
- Serine proteases, trypsin family, serine active site
Chain: L
Length: 55 amino acids
Theoretical weight: 6.03 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
Pfam: Coagulation Factor Xa inhibitory site
CATH: Laminin
Length: 55 amino acids
Theoretical weight: 6.03 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
- Canonical: P08709 (Residues: 150-204; Coverage: 12%)
Pfam: Coagulation Factor Xa inhibitory site
CATH: Laminin
