PDBe 5u09

X-ray diffraction
2.6Å resolution

High-resolution crystal structure of the human CB1 cannabinoid receptor


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
GlgA glycogen synthase; Cannabinoid receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 508 amino acids
Theoretical weight: 57.4 KDa
Source organisms: Expression system: Spodoptera frugiperda
  • Canonical: Q9V2J8 (Residues: 218-413; Coverage: 45%)
  • Canonical: P21554 (Residues: 90-301, 334-421; Coverage: 64%)
  • nullnull
Gene names: CNR, CNR1, PAB2292
Sequence domains: Glycosyl transferases group 1

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 50.652Å b: 80.381Å c: 81.178Å
α: 90° β: 91.72° γ: 90°
R R work R free
0.183 0.18 0.238
Expression system: Spodoptera frugiperda