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Abl1 SH3 pTyr89/134

X-ray diffraction
1.6Å resolution
PDB entry 5np2 coloured by chain, front view.
PDB entry 5np2 coloured by chain, side view.
PDB entry 5np2 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Tyrosine-protein kinase ABL1
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Multimeric state: monomeric
Accessible surface area: 3867.63 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-132602
Assembly 2
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Assembly Name: Tyrosine-protein kinase ABL1
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Multimeric state: monomeric
Accessible surface area: 4145.49 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-132602

Macromolecules

Tyrosine-protein kinase ABL1
Chains: A, B
Length: 61 amino acids
Theoretical weight: 6.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00519 (Residues: 64-120; Coverage: 5%)
Gene names: ABL, ABL1, JTK7
Pfam: SH3 domain
InterPro:
CATH: SH3 Domains
Tyrosine-protein kinase ABL1 in PDB entry 5np2, assembly 1, front view.
Tyrosine-protein kinase ABL1 in PDB entry 5np2, assembly 1, side view.
Tyrosine-protein kinase ABL1 in PDB entry 5np2, assembly 1, top view.
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