PDBe 5lxg

X-ray diffraction
2.73Å resolution

Revised crystal structure of the human adiponectin receptor 1 in an open conformation

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Adiponectin receptor protein 1 Chain: A
Molecule details ›
Chain: A
Length: 305 amino acids
Theoretical weight: 35.04 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q96A54 (Residues: 89-375; Coverage: 77%)
Gene names: ADIPOR1, CGI-45, PAQR1, TESBP1A
Sequence domains: Haemolysin-III related
V REGION HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 119 amino acids
Theoretical weight: 13.16 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins
V REGION LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 107 amino acids
Theoretical weight: 11.65 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: C2221
Unit cell:
a: 92.31Å b: 194.11Å c: 74.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.234
Expression systems:
  • Trichoplusia ni
  • Escherichia coli