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Structure of Sec23 and TANGO1 complex

Source organism: Homo sapiens
Biochemical function: metal ion binding
Biological process: COPII-coated vesicle budding
Cellular component: endoplasmic reticulum exit site

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00626
Domain description: Gelsolin repeat
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of Pfam domain PF00626 (Gelsolin repeat) in Protein transport protein Sec23A. Showing 1 copy in chain A.

PF04815
Domain description: Sec23/Sec24 helical domain
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of Pfam domain PF04815 (Sec23/Sec24 helical domain) in Protein transport protein Sec23A. Showing 1 copy in chain A.

PF08033
Domain description: Sec23/Sec24 beta-sandwich domain
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of Pfam domain PF08033 (Sec23/Sec24 beta-sandwich domain) in Protein transport protein Sec23A. Showing 1 copy in chain A.

PF04811
Domain description: Sec23/Sec24 trunk domain
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of Pfam domain PF04811 (Sec23/Sec24 trunk domain) in Protein transport protein Sec23A. Showing 1 copy in chain A.

PF04810
Domain description: Sec23/Sec24 zinc finger
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of Pfam domain PF04810 (Sec23/Sec24 zinc finger) in Protein transport protein Sec23A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR036465
Domain description: von Willebrand factor A-like domain superfamily
Occurring in:
  1. Protein transport protein Sec23A
IPR007123
Domain description: Gelsolin-like domain
Occurring in:
  1. Protein transport protein Sec23A
IPR029006
Domain description: ADF-H/Gelsolin-like domain superfamily
Occurring in:
  1. Protein transport protein Sec23A
IPR036180
Domain description: Gelsolin-like domain superfamily
Occurring in:
  1. Protein transport protein Sec23A
IPR037550
Domain description: Sec23, C-terminal
Occurring in:
  1. Protein transport protein Sec23A
IPR036175
Domain description: Sec23/Sec24 helical domain superfamily
Occurring in:
  1. Protein transport protein Sec23A
IPR006900
Domain description: Sec23/Sec24, helical domain
Occurring in:
  1. Protein transport protein Sec23A
IPR012990
Domain description: Sec23/Sec24 beta-sandwich
Occurring in:
  1. Protein transport protein Sec23A
IPR006896
Domain description: Sec23/Sec24, trunk domain
Occurring in:
  1. Protein transport protein Sec23A
IPR006895
Domain description: Zinc finger, Sec23/Sec24-type
Occurring in:
  1. Protein transport protein Sec23A
IPR036174
Domain description: Zinc finger, Sec23/Sec24-type superfamily
Occurring in:
  1. Protein transport protein Sec23A
IPR037364
Domain description: Protein transport protein Sec23
Occurring in:
  1. Protein transport protein Sec23A

Structure domains

CATH CATH domains
2.60.40.1670
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: beta-sandwich domain of Sec23/24
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of CATH domain 2.60.40.1670 (Immunoglobulin-like) in Protein transport protein Sec23A. Showing 1 copy in chain A.
1.20.120.730
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: Sec23/Sec24 helical domain
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of CATH domain 1.20.120.730 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Protein transport protein Sec23A. Showing 1 copy in chain A.
3.40.20.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Severin
Homology: Severin
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of CATH domain 3.40.20.10 (Severin) in Protein transport protein Sec23A. Showing 1 copy in chain A.
3.40.50.410
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: von Willebrand factor, type A domain
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of CATH domain 3.40.50.410 (Rossmann fold) in Protein transport protein Sec23A. Showing 1 copy in chain A.
2.30.30.380
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: Zn-finger domain of Sec23/24
Occurring in:
  1. Protein transport protein Sec23A
The deposited structure of PDB entry 5kyn contains 2 copies of CATH domain 2.30.30.380 (SH3 type barrels.) in Protein transport protein Sec23A. Showing 1 copy in chain A.

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