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Solution Structure of TAZ2-p53TAD

Source organisms:
Biochemical function: histone acetyltransferase activity
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

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EC 2.3.1.48: Histone acetyltransferase

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Systematic name:
Acetyl-CoA:[protein]-L-lysine acetyltransferase
Alternative Name(s):
  • Acetyl-CoA:histone acetyltransferase
  • Histone acetokinase
  • Histone acetylase
  • Histone transacetylase
  • Lysine acetyltransferase
  • Nucleosome-histone acetyltransferase
  • Protein lysine acetyltransferase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF18521
Domain description: Transactivation domain 2
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
The deposited structure of PDB entry 5hpd contains 1 copy of Pfam domain PF18521 (Transactivation domain 2) in Cellular tumor antigen p53. Showing 1 copy in chain A.

PF08563
Domain description: P53 transactivation motif
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
The deposited structure of PDB entry 5hpd contains 1 copy of Pfam domain PF08563 (P53 transactivation motif) in Cellular tumor antigen p53. Showing 1 copy in chain A.

PF02135
Domain description: TAZ zinc finger
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
The deposited structure of PDB entry 5hpd contains 1 copy of Pfam domain PF02135 (TAZ zinc finger) in Cellular tumor antigen p53. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000197
Domain description: Zinc finger, TAZ-type
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
IPR035898
Domain description: TAZ domain superfamily
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
IPR040926
Domain description: Cellular tumor antigen p53, transactivation domain 2
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
IPR013872
Domain description: p53 transactivation domain
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP
IPR013178
Domain description: Histone acetyltransferase Rtt109/CBP
Occurring in:
  1. Cellular tumor antigen p53; Histone lysine acetyltransferase CREBBP

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