PDBe 5h4z

X-ray diffraction
3.01Å resolution

Crystal structure of S202G mutant of human SYT-5 C2A domain

Released:
Source organism: Homo sapiens
Primary publication:
Structural analysis of Ca(2+)-binding pocket of synaptotagmin 5 C2A domain.
Int. J. Biol. Macromol. (2016)
PMID: 27793683

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptotagmin-5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 150 amino acids
Theoretical weight: 17.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00445 (Residues: 102-242; Coverage: 37%)
Gene name: SYT5
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 76.005Å b: 118.656Å c: 109.464Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.257
Expression system: Escherichia coli