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Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1

Electron Microscopy
3.07Å resolution
PDB entry 5h4p coloured by chain, front view.
PDB entry 5h4p coloured by chain, side view.
PDB entry 5h4p coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Assembly composition:
hetero 44-mer (preferred)
Entry contents: 41 distinct polypeptide molecules
3 distinct RNA molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero 44-mer
Accessible surface area: 619007.26 Å2
Buried surface area: 347241.82 Å2
Dissociation area: 1,288.47 Å2
Dissociation energy (ΔGdiss): 2.02 kcal/mol
Dissociation entropy (TΔSdiss): 14 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-135778

Macromolecules

Large ribosomal subunit protein uL2A
Chain: A
Length: 246 amino acids
Theoretical weight: 26.59 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX45 (Residues: 2-247; Coverage: 97%)
Gene names: RPL2A, RPL5B, YFR031BC, YFR031C-A
Pfam:
InterPro:
Large ribosomal subunit protein uL2A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL2A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL2A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL3
Chain: B
Length: 387 amino acids
Theoretical weight: 43.85 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P14126 (Residues: 1-387; Coverage: 100%)
Gene names: MAK8, RPL3, TCM1, YOR063W, YOR29-14
Pfam: Ribosomal protein L3
InterPro:
Large ribosomal subunit protein uL3 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL3 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL3 in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL4A
Chain: C
Length: 361 amino acids
Theoretical weight: 39.03 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P10664 (Residues: 2-362; Coverage: 100%)
Gene names: RPL2, RPL2A, RPL4A, YBR0315, YBR031W
Pfam:
InterPro:
Large ribosomal subunit protein uL4A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL4A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL4A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL18
Chain: D
Length: 297 amino acids
Theoretical weight: 33.76 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P26321 (Residues: 1-297; Coverage: 100%)
Gene names: LPI14W, RPL1, RPL1A, RPL5, YPL131W
Pfam:
InterPro:
Large ribosomal subunit protein uL18 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL18 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL18 in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL6A
Chain: E
Length: 176 amino acids
Theoretical weight: 20 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q02326 (Residues: 1-176; Coverage: 100%)
Gene names: RPL17A, RPL6A, YL16A, YML073C
Pfam: Ribosomal protein L6e
InterPro:
Large ribosomal subunit protein eL6A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL6A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL6A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL30A
Chain: F
Length: 244 amino acids
Theoretical weight: 27.69 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05737 (Residues: 1-244; Coverage: 100%)
Gene names: RPL6A, RPL7A, RPL8A, YGL076C, YL8A
Pfam:
InterPro:
Large ribosomal subunit protein uL30A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL30A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL30A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL8A
Chain: G
Length: 256 amino acids
Theoretical weight: 28.18 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P17076 (Residues: 1-256; Coverage: 100%)
Gene names: MAK7, RPL4A, RPL8A, YHL033C
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Large ribosomal subunit protein eL8A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL8A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL8A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL6A
Chain: H
Length: 191 amino acids
Theoretical weight: 21.61 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05738 (Residues: 1-191; Coverage: 100%)
Gene names: RPL8A, RPL9, RPL9A, YGL147C
Pfam: Ribosomal protein L6
InterPro:
Large ribosomal subunit protein uL6A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL6A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL6A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL5A
Chain: J
Length: 174 amino acids
Theoretical weight: 19.76 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0C0W9 (Residues: 1-174; Coverage: 100%)
Gene names: P8283.14, RP39A, RPL11A, RPL16A, YPR102C
Pfam:
InterPro:
Large ribosomal subunit protein uL5A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL5A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL5A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL13A
Chain: L
Length: 199 amino acids
Theoretical weight: 22.6 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q12690 (Residues: 1-199; Coverage: 100%)
Gene names: RPL13A, YDL082W
Pfam: Ribosomal protein L13e
InterPro:
Large ribosomal subunit protein eL13A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL13A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL13A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL14A
Chain: M
Length: 138 amino acids
Theoretical weight: 15.2 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P36105 (Residues: 1-138; Coverage: 100%)
Gene names: RPL14A, YKL006W, YKL153
Pfam:
InterPro:
Large ribosomal subunit protein eL14A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL14A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL14A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL15A
Chain: N
Length: 204 amino acids
Theoretical weight: 24.48 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05748 (Residues: 1-204; Coverage: 100%)
Gene names: RPL10A, RPL13A, RPL15A, YL10A, YLR029C
Pfam: Ribosomal L15
InterPro:
Large ribosomal subunit protein eL15A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL15A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL15A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL13A
Chain: O
Length: 199 amino acids
Theoretical weight: 22.25 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P26784 (Residues: 1-199; Coverage: 100%)
Gene names: RPL13, RPL16A, RPL21A, YIL133C
Pfam: Ribosomal protein L13
InterPro:
Large ribosomal subunit protein uL13A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL13A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL13A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein uL22A
Chain: P
Length: 184 amino acids
Theoretical weight: 20.59 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05740 (Residues: 1-184; Coverage: 100%)
Gene names: RPL17, RPL17A, RPL20A, YKL180W
Pfam: Ribosomal protein L22p/L17e
InterPro:
Large ribosomal subunit protein uL22A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL22A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL22A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL18A
Chain: Q
Length: 186 amino acids
Theoretical weight: 20.61 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX49 (Residues: 1-186; Coverage: 100%)
Gene names: RP28A, RPL18A, YOL120C
Pfam: Ribosomal protein 60S L18 and 50S L18e
InterPro:
Large ribosomal subunit protein eL18A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL18A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL18A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL19A
Chain: R
Length: 189 amino acids
Theoretical weight: 21.76 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX82 (Residues: 1-189; Coverage: 100%)
Gene names: RPL19A, RPL23A, YBR084BC, YBR084C-A, YL14A
Pfam: Ribosomal protein L19e
InterPro:
Large ribosomal subunit protein eL19A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL19A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL19A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL20A
Chain: S
Length: 172 amino acids
Theoretical weight: 20.48 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX23 (Residues: 1-172; Coverage: 100%)
Gene names: RPL18A, RPL18A2, RPL20A, YM9408.04C, YMR242C
Pfam: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
InterPro:
Large ribosomal subunit protein eL20A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL20A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL20A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL21A
Chain: T
Length: 160 amino acids
Theoretical weight: 18.28 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q02753 (Residues: 1-160; Coverage: 100%)
Gene names: RPL21A, URP1, YBR1401, YBR191W
Pfam: Ribosomal protein L21e
InterPro:
Large ribosomal subunit protein eL21A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL21A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL21A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL22A
Chain: U
Length: 121 amino acids
Theoretical weight: 13.71 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05749 (Residues: 1-121; Coverage: 100%)
Gene names: L2168, RPL22A, YLR061W
Pfam: Ribosomal L22e protein family
InterPro:
Large ribosomal subunit protein eL22A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL22A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL22A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein uL14A
Chain: V
Length: 137 amino acids
Theoretical weight: 14.49 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX41 (Residues: 1-137; Coverage: 100%)
Gene names: RPL17A, RPL17AA, RPL23A, YBL0713, YBL087C
Pfam: Ribosomal protein L14p/L23e
InterPro:
Large ribosomal subunit protein uL14A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL14A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL14A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL24A
Chain: W
Length: 155 amino acids
Theoretical weight: 17.66 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P04449 (Residues: 1-155; Coverage: 100%)
Gene names: RP29, RPL24A, RPL30A, YGL031C
Pfam: Ribosomal protein L24e
InterPro:
Large ribosomal subunit protein eL24A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL24A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL24A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein uL23
Chain: X
Length: 142 amino acids
Theoretical weight: 15.79 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P04456 (Residues: 1-142; Coverage: 100%)
Gene names: RPL25, YOL127W
Pfam:
InterPro:
Large ribosomal subunit protein uL23 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL23 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL23 in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein uL24A
Chain: Y
Length: 127 amino acids
Theoretical weight: 14.27 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05743 (Residues: 1-127; Coverage: 100%)
Gene names: L8300.4, RPL26, RPL26A, RPL33A, YLR344W
Pfam:
InterPro:
Large ribosomal subunit protein uL24A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL24A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL24A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL27A
Chain: Z
Length: 136 amino acids
Theoretical weight: 15.57 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0C2H6 (Residues: 1-136; Coverage: 100%)
Gene names: RPL27, RPL27A, YHR010W
Pfam: Ribosomal L27e protein family
InterPro:
Large ribosomal subunit protein eL27A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL27A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL27A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein uL15
Chain: a
Length: 149 amino acids
Theoretical weight: 16.76 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P02406 (Residues: 1-149; Coverage: 100%)
Gene names: CYH2, RPL28, YGL103W
Pfam: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
InterPro:
Large ribosomal subunit protein uL15 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL15 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL15 in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL29
Chain: b
Length: 59 amino acids
Theoretical weight: 6.69 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05747 (Residues: 1-59; Coverage: 100%)
Gene names: RPL29, YFR032BW, YFR032C-A, YL43
Pfam: Ribosomal L29e protein family
InterPro: Large ribosomal subunit protein eL29
Large ribosomal subunit protein eL29 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL29 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL29 in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL30
Chain: c
Length: 105 amino acids
Theoretical weight: 11.43 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P14120 (Residues: 1-105; Coverage: 100%)
Gene names: RPL30, RPL32, YGL030W
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Large ribosomal subunit protein eL30 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL30 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL30 in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL31A
Chain: d
Length: 113 amino acids
Theoretical weight: 12.98 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0C2H8 (Residues: 1-113; Coverage: 100%)
Gene names: D2478, RPL31A, RPL34, RPL34A, YDL075W
Pfam: Ribosomal protein L31e
InterPro:
Large ribosomal subunit protein eL31A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL31A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL31A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL32
Chain: e
Length: 130 amino acids
Theoretical weight: 14.81 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P38061 (Residues: 1-130; Coverage: 100%)
Gene names: RPL32, YBL0838, YBL092W
Pfam: Ribosomal protein L32
InterPro:
Large ribosomal subunit protein eL32 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL32 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL32 in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein eL33A
Chain: f
Length: 107 amino acids
Theoretical weight: 12.18 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05744 (Residues: 1-107; Coverage: 100%)
Gene names: LPI4W, P2625, RPL33A, RPL37A, YPL143W
Pfam: Ribosomal protein L35Ae
InterPro:
Large ribosomal subunit protein eL33A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL33A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL33A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL34A
Chain: g
Length: 121 amino acids
Theoretical weight: 13.67 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P87262 (Residues: 1-121; Coverage: 100%)
Gene names: RPL34A, YER056BC, YER056C-A
Pfam: Ribosomal protein L34e
InterPro:
Large ribosomal subunit protein eL34A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL34A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL34A in PDB entry 5h4p, assembly 1, top view.
Molecule details ›

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Large ribosomal subunit protein uL29A
Chain: h
Length: 120 amino acids
Theoretical weight: 13.94 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX84 (Residues: 1-120; Coverage: 100%)
Gene names: D1249, RPL35A, SOS1, YDL191W
Pfam: Ribosomal L29 protein
InterPro:
Large ribosomal subunit protein uL29A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein uL29A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein uL29A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL36A
Chain: i
Length: 100 amino acids
Theoretical weight: 11.15 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P05745 (Residues: 1-100; Coverage: 100%)
Gene names: RPL36A, RPL39A, YM9646.06, YMR194W
Pfam: Ribosomal protein L36e
InterPro:
Large ribosomal subunit protein eL36A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL36A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL36A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL37A
Chain: j
Length: 88 amino acids
Theoretical weight: 9.88 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P49166 (Residues: 1-88; Coverage: 100%)
Gene names: L9470.6, RPL35A, RPL37A, YLR185W
Pfam: Ribosomal protein L37e
InterPro:
Large ribosomal subunit protein eL37A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL37A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL37A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL38
Chain: k
Length: 78 amino acids
Theoretical weight: 8.85 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P49167 (Residues: 1-78; Coverage: 100%)
Gene names: L8543.2, RPL38, YLR325C
Pfam: Ribosomal L38e protein family
InterPro:
Large ribosomal subunit protein eL38 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL38 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL38 in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL39
Chain: l
Length: 51 amino acids
Theoretical weight: 6.36 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P04650 (Residues: 1-51; Coverage: 100%)
Gene names: J0360, RPL39, RPL46, SPB2, YJL189W
Pfam: Ribosomal L39 protein
InterPro:
Large ribosomal subunit protein eL39 in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL39 in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL39 in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL42A
Chain: o
Length: 106 amino acids
Theoretical weight: 12.25 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX27 (Residues: 1-106; Coverage: 100%)
Gene names: N1722, RPL41A, RPL42A, SCL41A, YNL162W
Pfam: Ribosomal protein L44
InterPro:
Large ribosomal subunit protein eL42A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL42A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL42A in PDB entry 5h4p, assembly 1, top view.
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Large ribosomal subunit protein eL43A
Chain: p
Length: 92 amino acids
Theoretical weight: 10.11 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P0CX25 (Residues: 1-92; Coverage: 100%)
Gene names: RPL43A, YP9499.02, YPR043W
Pfam: Ribosomal L37ae protein family
InterPro:
Large ribosomal subunit protein eL43A in PDB entry 5h4p, assembly 1, front view.
Large ribosomal subunit protein eL43A in PDB entry 5h4p, assembly 1, side view.
Large ribosomal subunit protein eL43A in PDB entry 5h4p, assembly 1, top view.
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60S ribosomal export protein NMD3
Chain: w
Length: 248 amino acids
Theoretical weight: 27.81 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P38861 (Residues: 155-402; Coverage: 48%)
Gene names: NMD3, YHR170W
Pfam:
InterPro:
60S ribosomal export protein NMD3 in PDB entry 5h4p, assembly 1, front view.
60S ribosomal export protein NMD3 in PDB entry 5h4p, assembly 1, side view.
60S ribosomal export protein NMD3 in PDB entry 5h4p, assembly 1, top view.
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Eukaryotic translation initiation factor 6
Chain: y
Length: 227 amino acids
Theoretical weight: 24.47 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q12522 (Residues: 1-227; Coverage: 93%)
Gene names: CDC95, LPZ15C, TIF6, YPR016C
Pfam: eIF-6 family
InterPro: Translation initiation factor IF6
Eukaryotic translation initiation factor 6 in PDB entry 5h4p, assembly 1, front view.
Eukaryotic translation initiation factor 6 in PDB entry 5h4p, assembly 1, side view.
Eukaryotic translation initiation factor 6 in PDB entry 5h4p, assembly 1, top view.
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Cytoplasmic 60S subunit biogenesis factor REH1
Chain: z
Length: 56 amino acids
Theoretical weight: 6.74 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06709 (Residues: 377-432; Coverage: 13%)
Gene names: REH1, YLR387C
Cytoplasmic 60S subunit biogenesis factor REH1 in PDB entry 5h4p, assembly 1, front view.
Cytoplasmic 60S subunit biogenesis factor REH1 in PDB entry 5h4p, assembly 1, side view.
Cytoplasmic 60S subunit biogenesis factor REH1 in PDB entry 5h4p, assembly 1, top view.
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RNA chain 1
Name: 25S ribosomal RNA
Representative chains: 1
Length: 3396 nucleotides
Theoretical weight: 1097.49 KDa
Rfam: Eukaryotic large subunit ribosomal RNA
25S ribosomal RNA in PDB entry 5h4p, assembly 1, front view.
25S ribosomal RNA in PDB entry 5h4p, assembly 1, side view.
25S ribosomal RNA in PDB entry 5h4p, assembly 1, top view.
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RNA chain 3
Name: 5S ribosomal RNA
Representative chains: 3
Length: 121 nucleotides
Theoretical weight: 38.95 KDa
Rfam: 5S ribosomal RNA
5S ribosomal RNA in PDB entry 5h4p, assembly 1, front view.
5S ribosomal RNA in PDB entry 5h4p, assembly 1, side view.
5S ribosomal RNA in PDB entry 5h4p, assembly 1, top view.
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RNA chain 4
Name: 5.8S ribosomal RNA
Representative chains: 4
Length: 158 nucleotides
Theoretical weight: 50.68 KDa
Rfam: 5.8S ribosomal RNA
5.8S ribosomal RNA in PDB entry 5h4p, assembly 1, front view.
5.8S ribosomal RNA in PDB entry 5h4p, assembly 1, side view.
5.8S ribosomal RNA in PDB entry 5h4p, assembly 1, top view.
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