› 5h1q

Electron Microscopy
3.3Å resolution

C. elegans INX-6 gap junction hemichannel

Released:
DOI: 10.2210/pdb5h1q/pdb
PDB entry 5h1q coloured by chain, front view.
PDB entry 5h1q coloured by chain, side view.
PDB entry 5h1q coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.
Oshima A, Tani K, Fujiyoshi Y
Nat Commun 7 13681 (2016)
PMID: 27905396
Related structures: EMD-9570

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Innexin-6 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 389 amino acids
Theoretical weight: 45.17 KDa
Source organism: Caenorhabditis elegans
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9U3N4 (Residues: 1-389; Coverage: 100%)
Gene names: C36H8.2, inx-6, opu-6
Sequence domains: Innexin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-9570
Expression system: Spodoptera frugiperda

Quick links

Citations

12 review citations

Cryo-EM: beyond the microscope.
Earl et al. (2017)
11 more

7 mentions without citation

On the molecular nature of large-pore channels.
Syrjanen et al. (2021)
6 more