PDBe 5ggt

X-ray diffraction
2.8Å resolution

PD-L1 in complex with BMS-936559 Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Programmed cell death 1 ligand 1 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
UniProt:
  • Canonical: Q9NZQ7 (Residues: 18-134; Coverage: 43%)
Gene names: B7H1, CD274, PDCD1L1, PDCD1LG1, PDL1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
IgG H chain Chain: H
Molecule details ›
Chain: H
Length: 235 amino acids
Theoretical weight: 25.03 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins
IGK@ protein Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P212121
Unit cell:
a: 37.199Å b: 91.555Å c: 164.156Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.211 0.269
Expression systems:
  • Escherichia coli-Pichia pastoris shuttle vector pPpARG4
  • Not provided