› 5euy

X-ray diffraction
2.06Å resolution

Thermostable aldehyde dehydrogenase from Pyrobaculum sp.1860 complexed with NADP+

Released:
DOI: 10.2210/pdb5euy/pdb
PDB entry 5euy coloured by chain, front view.
PDB entry 5euy coloured by chain, side view.
PDB entry 5euy coloured by chain, top view.
Source organism: Pyrobaculum ferrireducens
Primary publication:
NADP-Dependent Aldehyde Dehydrogenase from Archaeon Pyrobaculum sp.1860: Structural and Functional Features.
Bezsudnova EY, Petrova TE, Artemova NV, Boyko KM, Shabalin IG, Rakitina TV, Polyakov KM, Popov VO
Archaea 2016 9127857 (2016)
PMID: 27956891

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124588 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase domain-containing protein Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 491 amino acids
Theoretical weight: 54.46 KDa
Source organism: Pyrobaculum ferrireducens
Expression system: Escherichia coli
UniProt:
  • Canonical: G7VCG0 (Residues: 1-491; Coverage: 100%)
Gene name: P186_1147
Sequence domains: Aldehyde dehydrogenase family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NAP 8 x NAP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21212
Unit cell:
a: 184.77Å b: 208.05Å c: 165.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.232
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

An NAD-Specific 6-Hydroxy-3-Succinoyl-Semialdehyde-Pyridine Dehydrogenase from Nicotine-Degrading Agrobacterium tumefaciens Strain S33.
Shang et al. (2021)
2 more

1 mention without citation

NADP-Dependent Aldehyde Dehydrogenase from Archaeon Pyrobaculum sp.1860: Structural and Functional Features.
Bezsudnova et al. (2016)