Function and Biology

Isoform-specific inhibition of SUMO-dependent protein-protein interactions

Source organisms:
Biochemical function: cysteine-type endopeptidase inhibitor activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF11976
Domain description: Ubiquitin-2 like Rad60 SUMO-like
Occurring in:
  1. Small ubiquitin-related modifier 1
The deposited structure of PDB entry 5elj contains 1 copy of Pfam domain PF11976 (Ubiquitin-2 like Rad60 SUMO-like) in Small ubiquitin-related modifier 1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000010
Domain description: Cystatin domain
Occurring in:
  1. SUMO-Affirmer-S2D5
IPR000626
Domain description: Ubiquitin-like domain
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR022617
Domain description: Rad60/SUMO-like domain
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR046332
Domain description: Small ubiquitin-related modifier 1, Ubl domain
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR029071
Domain description: Ubiquitin-like domain superfamily
Occurring in:
  1. Small ubiquitin-related modifier 1
IPR046350
Domain description: Cystatin superfamily
Occurring in:
  1. SUMO-Affirmer-S2D5
IPR027214
Domain description: Cystatin
Occurring in:
  1. SUMO-Affirmer-S2D5

Structure domain

CATH CATH domain
3.10.450.10
Class: Alpha Beta
Architecture: Roll
Topology: Nuclear Transport Factor 2; Chain: A,
Homology: Nuclear Transport Factor 2; Chain: A,
Occurring in:
  1. SUMO-Affirmer-S2D5
The deposited structure of PDB entry 5elj contains 1 copy of CATH domain 3.10.450.10 (Nuclear Transport Factor 2; Chain: A,) in SUMO-Affirmer-S2D5. Showing 1 copy in chain A.