Function and Biology

Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1

Source organisms:
Biochemical function: nuclear import signal receptor activity
Biological process: protein import into nucleus
Cellular component: cytoplasm

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00514
Domain description: Armadillo/beta-catenin-like repeat
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 5ekf contains 7 copies of Pfam domain PF00514 (Armadillo/beta-catenin-like repeat) in Importin subunit alpha-1. Showing 7 copies in chain C [auth A].

PF16186
Domain description: Atypical Arm repeat
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 5ekf contains 1 copy of Pfam domain PF16186 (Atypical Arm repeat ) in Importin subunit alpha-1. Showing 1 copy in chain C [auth A].

PF01749
Domain description: Importin beta binding domain
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 5ekf contains 1 copy of Pfam domain PF01749 (Importin beta binding domain) in Importin subunit alpha-1. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR000225
Domain description: Armadillo
Occurring in:
  1. Importin subunit alpha-1
IPR032413
Domain description: Atypical Arm repeat
Occurring in:
  1. Importin subunit alpha-1
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Importin subunit alpha-1
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Importin subunit alpha-1
IPR024931
Domain description: Importin subunit alpha
Occurring in:
  1. Importin subunit alpha-1

Structure domain

CATH CATH domain
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Importin subunit alpha-1
The deposited structure of PDB entry 5ekf contains 1 copy of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Importin subunit alpha-1. Showing 1 copy in chain C [auth A].