PDBe 5e3u

X-ray diffraction
3.6Å resolution

Crystal structure of phosphatidylinositol-4-phosphate 5-kinase

Released:
Source organism: Danio rerio
Primary publication:
Mechanism of substrate specificity of phosphatidylinositol phosphate kinases.
Proc. Natl. Acad. Sci. U.S.A. (2016)
PMID: 27439870

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a Chain: A
Molecule details ›
Chain: A
Length: 372 amino acids
Theoretical weight: 42.26 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: Q503I3 (Residues: 56-427; Coverage: 67%)
Gene names: pip5k1a, pip5k1aa
Sequence domains: Phosphatidylinositol-4-phosphate 5-Kinase
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P43212
Unit cell:
a: 88.134Å b: 88.134Å c: 155.757Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.261
Expression system: Escherichia coli