PDBe 5c3t

X-ray diffraction
1.8Å resolution

PD-1 binding domain from human PD-L1

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Programmed cell death 1 ligand 1 Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 14.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NZQ7 (Residues: 18-134; Coverage: 43%)
Gene names: B7H1, CD274, PDCD1L1, PDCD1LG1, PDL1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2221
Unit cell:
a: 53.004Å b: 54.71Å c: 84.907Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.152 0.178
Expression system: Escherichia coli BL21(DE3)