PDBe 5wxh

X-ray diffraction
1.3Å resolution

Crystal structure of TAF3 PHD finger bound to H3K4me3

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transcription initiation factor TFIID subunit 3 Chains: A, C
Molecule details ›
Chains: A, C
Length: 63 amino acids
Theoretical weight: 7.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW Q5VWG9 (Residues: 853-915; Coverage: 7%)
Gene name: TAF3
Sequence domains: PHD-finger
Histone H3.1 Chains: D, P
Molecule details ›
Chains: D, P
Length: 7 amino acids
Theoretical weight: 819 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: NEW P68431 (Residues: 2-8; Coverage: 5%)
Gene names: H3FA, H3FB, H3FC, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P1
Unit cell:
a: 27.244Å b: 35.138Å c: 38.562Å
α: 82.96° β: 75.62° γ: 73.49°
R-values:
R R work R free
0.154 0.153 0.175
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided