PDBe 5wq4

X-ray diffraction
3Å resolution

Crystal structure of OPTN and linear diubiquitin complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 17.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: NEW P0CG48 (Residues: 533-684; Coverage: 22%)
Gene name: UBC
Sequence domains: Ubiquitin family
Optineurin Chains: C, D, E, F
Molecule details ›
Chains: C, D, E, F
Length: 97 amino acids
Theoretical weight: 11.17 KDa
Source organism: Mus musculus
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: NEW Q8K3K8 (Residues: 417-513; Coverage: 17%)
Gene name: Optn

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43
Unit cell:
a: 77.659Å b: 77.659Å c: 166.552Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.245 0.303
Expression system: Escherichia coli K-12