PDBe 5wiv

X-ray diffraction
2.14Å resolution

Structure of the sodium-bound human D4 Dopamine receptor in complex with Nemonapride

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D(4) dopamine receptor; Soluble cytochrome b562 Chain: A
Molecule details ›
Chain: A
Length: 422 amino acids
Theoretical weight: 45.31 KDa
Source organisms: Expression system: Insecta
UniProt:
  • Canonical: P0ABE7 (Residues: 24-128; Coverage: 99%)
  • Canonical: P21917 (Residues: 1-228, 335-419; Coverage: 75%)
  • nullnull
Gene names: DRD4, cybC
Sequence domains: Cytochrome b562

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: C2221
Unit cell:
a: 67.861Å b: 162.836Å c: 83.181Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.227
Expression system: Insecta