PDBe 5wer

X-ray diffraction
3.41Å resolution

Crystal Structure of TAPBPR and H2-Dd complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class I histocompatibility antigen, D-D alpha chain Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 277 amino acids
Theoretical weight: 32.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01900 (Residues: 26-301; Coverage: 81%)
Gene name: H2-D1
Sequence domains: Immunoglobulin C1-set domain
Beta-2-microglobulin Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Tapasin-related protein Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 394 amino acids
Theoretical weight: 42.28 KDa
Source organism: Homo sapiens
Expression system: Drosophila acanthoptera
UniProt:
  • Canonical: Q9BX59 (Residues: 22-410; Coverage: 86%)
  • Best match: Q9BX59-3 (Residues: 22-301)
Gene name: TAPBPL
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID, APS BEAMLINE 23-ID-B
Spacegroup: P31
Unit cell:
a: 169.05Å b: 169.05Å c: 139.41Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.243 0.239 0.269
Expression systems:
  • Escherichia coli BL21(DE3)
  • Drosophila acanthoptera