PDBe 5w6a

X-ray diffraction
1.74Å resolution

HLA-C*06:02 presenting ARTELYRSL

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, Cw-6 alpha chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 276 amino acids
Theoretical weight: 32.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q29963 (Residues: 25-300; Coverage: 81%)
Gene names: HLA-C, HLAC
Sequence domains:
Beta-2-microglobulin Chains: B, D
Molecule details ›
Chains: B, D
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Protein AATF Chains: E, F
Molecule details ›
Chains: E, F
Length: 9 amino acids
Theoretical weight: 1.11 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: Q9NY61 (Residues: 539-547; Coverage: 2%)
Gene names: AATF, CHE1, DED, HSPC277

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21
Unit cell:
a: 46.191Å b: 136.95Å c: 70.961Å
α: 90° β: 107.06° γ: 90°
R-values:
R R work R free
0.163 0.16 0.201
Expression systems:
  • Escherichia coli BL21
  • Not provided