PDBe 5ucj

X-ray diffraction
1.69Å resolution

Hsp90b N-terminal domain with inhibitors

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock protein HSP 90-beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 220 amino acids
Theoretical weight: 24.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P08238 (Residues: 1-218; Coverage: 30%)
Gene names: HSP90AB1, HSP90B, HSPC2, HSPCB
Sequence domains: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P65
Unit cell:
a: 129.464Å b: 129.464Å c: 106.357Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.174 0.197
Expression system: Escherichia coli