PDBe 5t2m

X-ray diffraction
2.8Å resolution

mPI3Kd IN COMPLEX WITH 7m

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Chain: A
Molecule details ›
Chain: A
Length: 939 amino acids
Theoretical weight: 107.77 KDa
Source organism: Mus musculus
Expression system: Insect cell expression vector pTIE1
UniProt:
  • Canonical: O35904 (Residues: 106-507, 509-1043; Coverage: 90%)
Gene name: Pik3cd
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2221
Unit cell:
a: 63.577Å b: 141.782Å c: 219.178Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.228 0.27
Expression system: Insect cell expression vector pTIE1