PDBe 5szj

X-ray diffraction
2.66Å resolution

Structure of human Rab10 in complex with the bMERB domain of Mical-cL

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Rab-10 Chain: A
Molecule details ›
Chain: A
Length: 202 amino acids
Theoretical weight: 22.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61026 (Residues: 1-200; Coverage: 100%)
Gene name: RAB10
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
MICAL C-terminal-like protein Chain: B
Molecule details ›
Chain: B
Length: 153 amino acids
Theoretical weight: 18.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6ZW33 (Residues: 534-683; Coverage: 22%)
Gene name: MICALCL
Sequence domains: Bivalent Mical/EHBP Rab binding domain

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 153.68Å b: 61.87Å c: 55.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.224 0.266
Expression system: Escherichia coli