PDBe 5ou8

X-ray diffraction
2.5Å resolution

Crystal structure of Glycoprotein VI in complex with collagen-peptide (GPO)5

Released:
Source organism: Homo sapiens
Entry authors: Feitsma LJ, Huizinga EG

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Platelet glycoprotein VI Chains: A, B
Molecule details ›
Chains: A, B
Length: 181 amino acids
Theoretical weight: 19.72 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: Gene name: GP6
Sequence domains: Immunoglobulin domain
Collagen alpha-1(I) chain Chains: C, D, E
Molecule details ›
Chains: C, D, E
Length: 15 amino acids
Theoretical weight: 1.35 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: NEW P02452 (Residues: 1178-1192; Coverage: 1%)
Gene name: COL1A1

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P41212
Unit cell:
a: 59.97Å b: 59.97Å c: 313.212Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.208 0.257
Expression systems:
  • Homo sapiens
  • Not provided