PDBe 5opi

X-ray diffraction
3.3Å resolution

Crystal structure of the TAPBPR-MHC I peptide editing complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class I histocompatibility antigen, D-B alpha chain Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 32.33 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P01899 (Residues: 25-300; Coverage: 82%)
Gene name: H2-D1
Sequence domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
TAP binding protein-like variant Chain: C
Molecule details ›
Chain: C
Length: 373 amino acids
Theoretical weight: 39.7 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: NEW Q53GH5 (Residues: 33-401; Coverage: 83%)
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P6522
Unit cell:
a: 205.04Å b: 205.04Å c: 121.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.245 0.242 0.303
Expression systems:
  • Escherichia coli
  • Spodoptera frugiperda