PDBe 5nsa

X-ray diffraction
1.27Å resolution

Beta domain of human transcobalamin bound to Co-beta-[2-(2,4-difluorophenyl)ethinyl]cobalamin

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcobalamin-2 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 11.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P20062 (Residues: 325-427; Coverage: 25%)
Gene names: TC2, TCN2
Sequence domains: Domain of unknown function (DUF4430)

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 61.721Å b: 62.298Å c: 33.762Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.144 0.179
Expression system: Spodoptera frugiperda