PDBe 5nq1

X-ray diffraction
2.14Å resolution

Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting DFEREGYSL

Released:
Entry authors: Rizkallah PJ, Tungatt K, Sewell AK

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
MHC class I antigen Chains: A, D
Molecule details ›
Chains: A, D
Length: 276 amino acids
Theoretical weight: 31.68 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: B1PJV3 (Residues: 22-296; Coverage: 81%)
Gene name: SLA-1
Sequence domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Nucleoprotein Chains: C, F
Molecule details ›
Chains: C, F
Length: 9 amino acids
Theoretical weight: 1.12 KDa
Source organism: unidentified influenza virus
Expression system: Not provided
UniProt:
  • Canonical: Q9Q0U8 (Residues: 290-298; Coverage: 2%)
Gene name: NP

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P1
Unit cell:
a: 59.388Å b: 60.288Å c: 65.645Å
α: 81.24° β: 67.59° γ: 67.94°
R-values:
R R work R free
0.223 0.22 0.283
Expression systems:
  • Escherichia coli
  • Not provided