PDBe 5nks

X-ray diffraction
1.8Å resolution

Human Dihydropyrimidinase-related Protein 4 (DPYSL4, CRMP3, ULIP-4)

Released:
Source organism: Homo sapiens
Entry authors: Mathea S, Elkins JM, Strain-Damerell C, Salah E, Borkowska O, Chalk R, Burgess-Brown N, Pinkas DM, von Delft F, Krojer T, Arrowsmith CH, Edwards AM, Bountra C, Knapp S

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydropyrimidinase-related protein 4 Chain: A
Molecule details ›
Chain: A
Length: 573 amino acids
Theoretical weight: 62.04 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: NEW O14531 (Residues: 1-572; Coverage: 100%)
Gene names: CRMP3, DPYSL4, ULIP4
Sequence domains: Amidohydrolase family

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: I222
Unit cell:
a: 80.47Å b: 102.65Å c: 116.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.155 0.2
Expression system: Spodoptera frugiperda