PDBe 5njk

X-ray diffraction
3.13Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein numb homolog Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 156 amino acids
Theoretical weight: 17.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: NEW P49757 (Residues: 20-175; Coverage: 24%)
Gene names: C14orf41, NUMB
Sequence domains: Phosphotyrosine interaction domain (PTB/PID)
ALA-TYR-ILE-GLY-PRO-PTR-LEU Chains: G, H, I, J, K, M
Molecule details ›
Chains: G, H, I, J, K, M
Length: 7 amino acids
Theoretical weight: 876 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P212121
Unit cell:
a: 75.27Å b: 81.87Å c: 235.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.23 0.26
Expression systems:
  • Escherichia coli BL21
  • Not provided