PDBe 5ncy

X-ray diffraction
1.9Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Chain: A
Molecule details ›
Chain: A
Length: 939 amino acids
Theoretical weight: 107.74 KDa
Source organism: Mus musculus
Expression system: Insect cell expression vector pTIE1
UniProt:
  • Canonical: O35904 (Residues: 106-507, 509-1043; Coverage: 90%)
Gene name: Pik3cd
Sequence domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 140.989Å b: 64.549Å c: 116.013Å
α: 90° β: 103.59° γ: 90°
R-values:
R R work R free
0.224 0.222 0.264
Expression system: Insect cell expression vector pTIE1