PDBe 5mwx

X-ray diffraction
1.29Å resolution

Galectin-1 in Complex with Ligand JB60

Released:
Source organism: Homo sapiens
Entry authors: Grimm C, Bechold J

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P212121
Unit cell:
a: 43.26Å b: 58.25Å c: 111.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.205
Expression system: Escherichia coli