PDBe 5mfa

X-ray diffraction
1.2Å resolution

Function and Biology Details

Reaction catalysed:
Cl(-) + H(2)O(2) + H(+) = HClO + H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myeloperoxidase Chain: A
Molecule details ›
Chain: A
Length: 697 amino acids
Theoretical weight: 79.05 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P05164 (Residues: 49-745; Coverage: 100%)
Gene name: MPO
Sequence domains: Animal haem peroxidase

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 106.152Å b: 109.151Å c: 83.961Å
α: 90° β: 122.66° γ: 90°
R-values:
R R work R free
0.124 0.123 0.143
Expression system: Cricetulus griseus