PDBe 5jkk

X-ray diffraction
1.6Å resolution

Crystal structure of the negatively supercharged variant Ftn(neg) of human heavy chain ferritin

Released:
Source organism: Homo sapiens
Entry authors: Kuenzle M, Beck T

Function and Biology Details

Reaction catalysed:
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin heavy chain Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 183 amino acids
Theoretical weight: 21.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02794 (Residues: 1-183; Coverage: 100%)
Gene names: FTH, FTH1, FTHL6, OK/SW-cl.84, PIG15
Sequence domains: Ferritin-like domain

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P23
Unit cell:
a: 180.98Å b: 180.98Å c: 180.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.125 0.124 0.143
Expression system: Escherichia coli