PDBe 5jer

X-ray diffraction
2.91Å resolution

Structure of Rotavirus NSP1 bound to IRF-3

Released:
Source organisms:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero octamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Non-structural protein 1 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 19 amino acids
Theoretical weight: 2.26 KDa
Source organism: Rotavirus A
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99FX5 (Residues: 478-496; Coverage: 4%)
Interferon regulatory factor 3 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 242 amino acids
Theoretical weight: 26.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14653 (Residues: 189-427; Coverage: 56%)
Gene name: IRF3
Sequence domains: Interferon-regulatory factor 3
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 67.772Å b: 107.924Å c: 135.647Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.21 0.25
Expression system: Escherichia coli