PDBe 5jeo

X-ray diffraction
1.72Å resolution

Phosphorylated Rotavirus NSP1 in complex with IRF-3

Source organisms:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Non-structural protein 1 Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.34 KDa
Source organism: Rotavirus A
Expression system: Escherichia coli
  • Canonical: Q99FX5 (Residues: 478-496; Coverage: 4%)
Interferon regulatory factor 3 Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 26.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q14653 (Residues: 189-427; Coverage: 56%)
Gene name: IRF3
Sequence domains: Interferon-regulatory factor 3
Structure domains: Tumour Suppressor Smad4

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P3221
Unit cell:
a: 72.982Å b: 72.982Å c: 127.551Å
α: 90° β: 90° γ: 120°
R R work R free
0.17 0.169 0.183
Expression system: Escherichia coli