PDBe 5j26

X-ray diffraction
2.5Å resolution

Crystal structure of a 53BP1 Tudor domain in complex with a ubiquitin variant

Released:
Source organism: Homo sapiens
Entry authors: Wan L, Canny M, Juang YC, Durocher D, Sicheri F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin Chain: B
Molecule details ›
Chain: B
Length: 76 amino acids
Theoretical weight: 8.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62987 (Residues: 1-75; Coverage: 59%)
Gene names: UBA52, UBCEP2
Sequence domains: Ubiquitin family
TP53-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12888 (Residues: 1487-1603; Coverage: 6%)
Gene name: TP53BP1
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P212121
Unit cell:
a: 39.531Å b: 47.768Å c: 94.237Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.231 0.287
Expression system: Escherichia coli