PDBe 5iz8

X-ray diffraction
3.06Å resolution

Protein-protein interaction

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Adenomatous polyposis coli protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 354 amino acids
Theoretical weight: 39.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P25054 (Residues: 407-751; Coverage: 12%)
Gene names: APC, DP2.5
Sequence domains: Armadillo/beta-catenin-like repeat
ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2 Chains: C, D
Molecule details ›
Chains: C, D
Length: 9 amino acids
Theoretical weight: 670 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P6522
Unit cell:
a: 114.073Å b: 114.073Å c: 308.295Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.215 0.213 0.253
Expression systems:
  • Escherichia coli
  • Not provided