PDBe 5ih5

X-ray diffraction
2.25Å resolution

Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A

Released:

Function and Biology Details

Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + [tau protein] = ADP + [tau protein] phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase I isoform delta Chain: A
Molecule details ›
Chain: A
Length: 294 amino acids
Theoretical weight: 34.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P48730 (Residues: 1-294; Coverage: 71%)
Gene names: CSNK1D, HCKID
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P3121
Unit cell:
a: 65.07Å b: 65.07Å c: 151.48Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.241 0.24 0.26
Expression system: Escherichia coli BL21(DE3)