PDBe 5hp0

Solution NMR

Solution Structure of TAZ2-p53AD2

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CREB-binding protein; Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.71 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW P04637 (Residues: 37-61; Coverage: 6%)
  • Canonical: NEW P45481 (Residues: 1764-1855; Coverage: 4%)
  • nullnull
Gene names: Cbp, Crebbp, P53, TP53
Sequence domains: TAZ zinc finger
Structure domains: TAZ domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing, molecular dynamics
Chemical shifts: BMR30003  
Expression system: Escherichia coli BL21(DE3)