PDBe 5how

X-ray diffraction
2.3Å resolution

X-ray crystallographic structure of an Abeta 17-36 beta-hairpin. LV(PHI)FAEDCGSNKCAII(SAR)L(ORN)V


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assemblies composition:
homo 12-mer
homo trimer (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
P3(40) Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 21 amino acids
Theoretical weight: 2.37 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P05067 (Residues: 688-707; Coverage: 3%)
Gene names: A4, AD1, APP

Ligands and Environments

No bound ligands

3 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P6122
Unit cell:
a: 97.31Å b: 97.31Å c: 97.621Å
α: 90° β: 90° γ: 120°
R R work R free
0.236 0.234 0.262
Expression system: Not provided