PDBe 5hou

Solution NMR

Solution Structure of p53TAD-TAZ1

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CREB-binding protein; Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.11 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04637 (Residues: 1-61, 69-69; Coverage: 16%)
  • Canonical: P45481 (Residues: 341-439; Coverage: 4%)
  • nullnull
Gene names: Cbp, Crebbp, P53, TP53
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: simulated annealing, molecular dynamics
Chemical shifts: BMR30002  
Expression system: Escherichia coli BL21(DE3)