PDBe 5hns

X-ray diffraction
2.45Å resolution

Structure of glycosylated NPC1 luminal domain C

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NPC intracellular cholesterol transporter 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 244 amino acids
Theoretical weight: 27.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15118 (Residues: 387-618; Coverage: 19%)
Gene name: NPC1

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2221
Unit cell:
a: 87.89Å b: 115.91Å c: 147.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.224 0.238
Expression system: Homo sapiens